Professor Erasmus University Medical Center Dordrecht, Netherlands
Disclosure(s):
Sebastian J.C.M.M Neggers, MD, PhD: recordati: Advisory Board (), Grant Recipient (), Honorarium Recipient ()
Emerging data on GIP receptor antagonists shows promising results for paradoxical GH secretion in a subset of patients, suggesting a targeted treatment avenue. Meanwhile treatment with pasireotide may benefit patients beyond hormonal control, with evidence of tumor shrinkage and long-term safety. Lastly, ketone body infusion may be a novel metabolic approach in the treatment of acromegaly.
Learning Objectives:
Understand how GIP receptor blockade can improve metabolic regulation.
Recognize pasireotide’s structural effects on pituitary adenoma
Explore ketone body infusion as a novel metabolic therapy in acromegaly.
Identify immune pathways influencing somatostatin analog response.
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