MASSACHUSETTS GENERAL HOSPITAL Boston, Massachusetts, United States
Better understanding of the PTH/PTHrP and GNAS signaling pathways have revealed key roles in a wide variety of biological processes. This session highlights new understandings in the basic mechanisms and clinical
Learning Objectives:
Gain insights into the molecular pathways and phenotypic spectrum of pseudohypoparathyroidism (PHP) and acrodystosis.
Examine the pathophysiology and clinical implications of ectopic ossification in disorders involving inactivating mutations in PTH/PTHrP and GNAS, and discuss emerging therapeutic approaches.
Examine the multifaceted role of GNAS mutations in obesity and metabolic disorders, highlighting translational research and potential interventions.
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