ORF48 - Reprogramming Steroid and Nuclear Receptor Networks in Cancer: From Chromatin Crosstalk to Targets

ORF Chair-Primary(s)

• MS

  Matthew Sikora, PhD (he/him/his)

  Associate Professor
  Pathology
  University of Colorado Anschutz Medical Campus
  Aurora, CO, United States

  Disclosure information not submitted.

Presentations:

• 1:45 PM - 1:50 PM CT

  Mapping the Functional Landscape of the Farnesoid X Receptor N-Terminal Domain
  

  Rapid and Poster Presenter: Thilini Thusharika Pulahinge, Bsc (she/her/hers) – Penn State University

  Senior Author/Primary Investigator: Denise Okafor, PhD (she/her/hers) – Pennsylvania State University

  Co-Author: Priscilla Villalona, Bsc – Penn State University
• 1:50 PM - 1:55 PM CT

  The Structural Basis of Ligand-Specific Estrogen Receptor Alpha Transcriptional Rewiring
  

  Rapid and Poster Presenter: Emma Fink, BS – Loyola University Chicago

  Senior Author/Primary Investigator: Sean W. Fanning, PhD (he/him/his) – LOYOLA UNIVERSITY
• 1:55 PM - 2:00 PM CT

  Estrogen and Androgen Receptor Crosstalk at Cancer Risk Loci Regulates Hormone-Dependent IGFBP5 Expression in ER-Positive Breast Cancer
  

  Rapid and Poster Presenter: Rebekah Badayos Hormigos, MS Molecular Biology and Biotechnology (she/her/hers) – UNIVERSITY OF THE PHILIPPINES DILIMAN

  Senior Author/Primary Investigator: Pia D. Bagamasbad, PhD – University of the Philippines Diliman
• 2:00 PM - 2:15 PM CT

  Targeting Steroid Hormone Receptor Crosstalk for Novel Therapeutic Strategies in Endometrial Cancer
  

  Oral Abstract Presenter: Grace Lee, MD (she/her/hers) – University of Chicago

  Co-Author: Ibrahim Al-Sawalha, MD – University of Chicago

  Co-Author: Diane Yamada, MD – University of Chicago Medicine

  Co-Author: Gini Fleming, MD – University of Chicago Medicine

  Co-Author: Katherine Kurnit, MD, MPH – University of Chicago Medicine

  Senior Author/Primary Investigator: Sridevi Challa, PhD – University of Chicago

  Co-Author: Suzanne Conzen, MD, M.Sc. – UT Southwestern Medical Center
• 2:15 PM - 2:30 PM CT

  Ligand and Context Specific Estrogen Receptor Interactomes
  

  Oral Abstract Presenter: David Robert Zak, B.S. (he/him/his) – LOYOLA UNIVERSITY OF CHICAGO

  Senior Author/Primary Investigator: Sean W. Fanning, PhD (he/him/his) – LOYOLA UNIVERSITY

  Co-Author: Sarah Flury, n/a – Loyola University Chicago

  Co-Author: Toni. R Pak, n/a – Loyola University Chicago
• 2:30 PM - 2:45 PM CT

  Progesterone Receptor Reprogramming and Coregulator Recruitment Drive the Transcriptional Landscape of Paclitaxel Resistance in ER+ Breast Cancer Cells
  

  Co-Author: Thu Truong, PhD – University of Minnesota

  Co-Author: Marygrace Trousdell, BS – Cold Spring Harbor Laboratory

  Co-Author: Rebecca Anderson, BS – Cold Spring Harbor Laboratory

  Co-Author: Kyla Hagen, BS – UNIVERSITY OF MINNESOTA

  Co-Author: Nuri Temiz, PhD – University of Minnesota

  Co-Author: Noelle Gillis, PhD (she/her/hers) – UNIVERSITY OF VERMONT AND

  Co-Author: Marie Antony, PhD – University of Minnesota

  Co-Author: Klara Noble-Orcutt, BS – University of Minnesota

  Co-Author: Michael Ciccone, BS – Cold Spring Harbor Laboratory

  Co-Author: Fatemah Dewji, M.S. (she/her/hers) – University of Minnesota

  Co-Author: Amy R. Dwyer, PhD (she/her/hers) – UNIVERSITY OF ADELAIDE

  Co-Author: Zohar Sachs, MD, PhD (she/her/hers) – University of Minnesota

  Co-Author: Carol A. Lange, PhD (she/her/hers) – University of Minnesota

  Co-Author: Camila dos Santos, PhD (she/her/hers) – Cold Spring Harbor Laboratory

  Oral Abstract Presenter: Julie H. Ostrander, PhD (she/her/hers) – University of Minnesota
• 2:45 PM - 3:00 PM CT

  Formation of Mineralocorticoid and Glucocorticoid Receptor Heterodimers Results in Dissociative Corticosteroid Signalling
  

  Oral Abstract Presenter: Erin Faught, PhD – Radboud University

  Co-Author: Marcel Schaaf, PhD – Institute of Biology, Leiden University, The Netherlands
• 3:00 PM - 3:15 PM CT

  Investigating Progesterone Receptor-Driven Actions in Therapy-Resistant ER+ Breast Cancer
  

  Oral Abstract Presenter: Anna M. Koppin, BS (she/her/hers) – UNIVERSITY OF MINNESOTA

  Senior Author/Primary Investigator: Thu Truong, PhD – University of Minnesota