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Carmella Evans-Molina, MD, PhD

Professor
Indiana University
Indianapolis, IN, United States

Dr. Carmella Evans-Molina is the Eli Lilly Professor of Pediatric Diabetes at the Indiana University (IU) School of Medicine in Indianapolis, IN, where she serves as Director of the IU Center for Diabetes and Metabolic Diseases and Program Leader for the Diabetes Research Group in the Herman B Wells Center for Pediatric Research. She is a Staff Physician at the Roudebush Veteran's Affairs (VA) Medical Center. Dr. Evans-Molina’s research is focused on understanding the molecular and signaling pathways within pancreatic β cells that drive the transition from a compensated state of euglycemia to a decompensated state of hyperglycemia in both type 1 (T1D) and type 2 diabetes (T2D). Her basic science studies have demonstrated that compromised calcium signaling within the β cell secretory pathway impairs insulin secretion, processing, and trafficking, activates organelle-specific stress pathways, and promotes β cell immunogenicity. Translational and clinical projects in her lab harness knowledge gained from studying stress pathways within the β cell to develop miRNA and protein biomarkers to inform T1D screening strategies and identify targets for disease-modifying therapies. Her research is funded by the NIH, the VA Research Program, Breakthrough T1D, and the Helmsley Charitable Trust. She is an investigator in the NIH-funded Type 1 Diabetes TrialNet, where she will serve as the Vice-Chair of network beginning in June 2026. She is also a member of the NIH-funded RADIANT and the TIDAPC/DREAM consortia. Dr. Evans-Molina is a Co-Executive Director of the Network for Pancreatic Organ Donors with Diabetes (nPOD), Co-PI of the NIH-funded Integrated Islet Distribution Program, and an Associate Editor for Diabetes. 

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