SY36 - Obesity, Metabolism, and Cancer: Mechanisms and Clinical Impact

Symposium Chair(s)

• JB

  John Blenis, PhD

  Professor
  Weill Cornell Medicine
  New York, NY, United States

  Disclosure(s): No financial relationships to disclose

Obesity is a major, modifiable risk factor for cancer, influencing tumor initiation, progression, and therapy response. While obesity worsens cancer incidence and outcomes for many cancers, how weight loss improves tumor risk and progression remains uncertain. This session will highlight emerging mechanisms linking obesity, metabolism, and cancer biology, and examine the impact of weight loss through lifestyle, pharmacologic, and surgical interventions. Attendees will gain insights into prevention strategies and therapeutic opportunities.

Presentations:

• 4:30 PM - 4:54 PM CT

  How Does Weight Loss Through Bariatric Surgery, GLP1 Agonism, and Calorie Restriction Affect Tumor Outcomes?
  

  Symposium Speaker: Stephen Hursting
• 4:54 PM - 5:16 PM CT

  Obesity in Breast Cancer and Clinical Trial
  

  Symposium Speaker: Neil Iyengar, MD – EMORY UNIVERSITY
• 5:16 PM - 5:38 PM CT

  What Is the Evidence for Using Weight Loss as Anti-cancer Strategies
  

  Symposium Speaker: Andrew Renehan
• 5:38 PM - 6:00 PM CT

  Adipose Tissue Dysfunction and Cancer Risks
  

  Symposium Speaker: Philipp E. Scherer, PhD – University of TX Southwestern Medical Center