SY59 - Glial Cells as Active Modulators of the Hypothalamic–Pituitary–Gonadal Axis

Tuesday, June 16, 2026

9:00 AM - 10:30 AM CT

Location: Room W183A

Symposium Chair(s)

Waljit Dhillo, Professor

Doctor
Department of Metabolism, Digestion and Reproduction
Imperial College London
London, United Kingdom

Disclosure(s): No financial relationships to disclose
Ursula Kaiser, MD

Professor of Medicine
Brigham and Women's Hospital, Harvard Medical School
Boston, MA, United States

Disclosure(s): No financial relationships to disclose

Disclosure(s):

Waljit Dhillo, BSc, MBBS, PhD, FRCP, FMedSci: No financial relationships to disclose

Ursula Kaiser, MD: No financial relationships to disclose

Mauricio D. Dorfman, PhD: No financial relationships to disclose

Sue Moenter, PhD: No financial relationships to disclose

This session will explore how glial cells, including tanycytes, astrocytes, and microglia, actively modulate the hypothalamic-pituitary-gonadal axis. Speakers will highlight molecular and cellular mechanisms linking glial activity to metabolism, inflammation, and reproduction, providing new insights into fertility, puberty, and reproductive aging.

Presentations:

9:00 AM - 9:30 AM CT

Microglial Inflammation and Its Impact on the HPG Axis
Symposium Speaker: Mauricio D. Dorfman, PhD – University of Washington
9:30 AM - 10:00 AM CT

Neuron-Astroglia Interactions Shaping GnRH Neuron Activity
Symposium Speaker: Sue Moenter, PhD – University of Michigan
10:00 AM - 10:30 AM CT

Tanycyte-Mediated Regulation of GnRH release
Symposium Speaker: Vincent Prevot, PhD – INSERM U1172