ORF12 - New Biomarkers, Surgical Trends, and Therapeutic Paradigms in Differentiated and Medullary Thyroid Cancer

ORF Chair-Primary(s)

• JC

  Julie Chen (she/her/hers)

  Clinical Associate Professor
  Division of Endocrinology
  STANFORD University MEDICAL Center
  Palo Alto, CA, United States

  Disclosure information not submitted.

This session combines translational and clinical research exploring the utility of new biomarkers to diagnose and predict prognosis in differentiated thyroid cancer, novel surgical trends and advances in medullary thyroid cancer

Presentations:

• 1:45 PM - 1:50 PM CT

  Medullary Thyroid Carcinoma Mimicking Acute Leukemia: Bone Marrow Metastasis with Rapid Hematologic Recovery Following Selpercatinib in a RET-Mutant Tumor
  

  Rapid and Poster Presenter: Harshani Yarlagadda, MD

  Co-Author: Tajana Juranovic, MD – West Virginia University

  Co-Author: Sidra Najeeb, MD, MS. – West Virginia University Cancer Institute

  Senior Author/Primary Investigator: Mehjabeen Sadiq, MD – WEST VIRGINIA UNIVERSITY

  Co-Author: Mehjabeen Sadiq, MD – WEST VIRGINIA UNIVERSITY
• 1:50 PM - 1:55 PM CT

  A Novel Genetic Cause of Familial Medullary Thyroid Carcinoma: Intragenic SLC30A9 Deletion and Translation Reinitiation
  

  Rapid and Poster Presenter: Donato Iacovazzo, MD, PhD, FRCPath – Queen Mary University of London

  Co-Author: Federica Begalli, n/a – Centre for Endocrinology, William Harvey Research Institute, Queen Mary University of London

  Co-Author: Oniz Suleyman, n/a – Centre for Endocrinology, William Harvey Research Institute, Queen Mary University of London

  Co-Author: Márton Doleschall, n/a – Molecular Medicine Research Group, Eötvös Loránd Research Network and Semmelweis University

  Co-Author: Kevin Ashelford, n/a – Division of Cancer and Genetics, Cardiff University School of Medicine

  Co-Author: Sherine Awad Mahmoud, n/a – Medical Research Council Metabolic Diseases Unit, Institute of Metabolic Science, University of Cambridge

  Co-Author: Sayka Barry, n/a – Centre for Endocrinology, William Harvey Research Institute, Queen Mary University of London

  Co-Author: Claudia P. Cabrera, n/a – Centre for Translational Bioinformatics, William Harvey Research Institute, Queen Mary University of London

  Co-Author: Kevin Colclough, n/a – Exeter Genomics Laboratory, Royal Devon and Exeter NHS Foundation Trust

  Co-Author: Alexandra Csábi, n/a – Molecular Medicine Research Group, Eötvös Loránd Research Network and Semmelweis University

  Co-Author: Jawid M. Fatih, n/a – Department of Molecular and Human Genetics, Baylor College of Medicine

  Co-Author: Mira Gandhi, n/a – Department of Molecular and Human Genetics, Baylor College of Medicine

  Co-Author: Christopher M. Grochowski, n/a – Department of Molecular and Human Genetics, Baylor College of Medicine

  Co-Author: Charlotte L. Hall, n/a – Centre for Endocrinology, William Harvey Research Institute, Queen Mary University of London

  Co-Author: Kesson Magid, n/a – Centre for Endocrinology, William Harvey Research Institute, Queen Mary University of London

  Co-Author: Monika Mozere, n/a – Department of Renal Medicine, University College London

  Co-Author: Martina Owens, n/a – Exeter Genomics Laboratory, Royal Devon and Exeter NHS Foundation Trust

  Co-Author: Luka Ozretić, n/a – Department of Cellular Pathology, Royal Free London NHS Foundation Trust

  Co-Author: Attila Patócs, n/a – Department of Molecular Genetics and the National Tumour Biology Laboratory, National Institute of Oncology

  Co-Author: Jaya Punetha, n/a – Department of Molecular and Human Genetics, Baylor College of Medicine

  Co-Author: Horia Stanescu, n/a – Department of Renal Medicine, University College London

  Co-Author: Mehmet Tekman, n/a – Department of Renal Medicine, University College London

  Co-Author: Laura E. Thomas, n/a – Institute of Life Science 1, Swansea University

  Co-Author: Claudia M.B. Carvalho, n/a – Department of Molecular and Human Genetics, Baylor College of Medicine

  Co-Author: Martin Franke, n/a – Centro Andaluz de Biología del Desarrollo (CABD), Consejo Superior de Investigaciones Científicas/Universidad Pablo de Olavide

  Co-Author: Robert Kleta, n/a – Department of Renal Medicine, University College London

  Co-Author: James R. Lupski, n/a – Department of Molecular and Human Genetics, Baylor College of Medicine

  Co-Author: Julian R. Sampson, n/a – Division of Cancer and Genetics, Cardiff University School of Medicine

  Co-Author: Laura De Marinis, Professor – Catholic University of Rome

  Senior Author/Primary Investigator: Marta Korbonits, MD PhD (she/her/hers) – Centre for Endocrinology, William Harvey Research Institute, Queen Mary University of London
• 1:55 PM - 2:00 PM CT

  Trends in Surgical Management of Differentiated Thyroid Cancer in Hawaii Following the 2015 American Thyroid Association Guidelines
  

  Senior Author/Primary Investigator: Stacey Woodruff, MD – John A Burns School of Medicine

  Rapid and Poster Presenter: Ryan Nguyen, MD

  Co-Author: Ryan Nguyen, MD

  Co-Author: Kameko M. Karasaki, MD (she/her/hers) – John A Burns School of Medicine

  Co-Author: Brenda Y. Hernandez, MPH, PhD – University of Hawaii
• 2:00 PM - 2:15 PM CT

  Genetic Variants in the N-Degron Pathway Gene NTAN1 Destabilize Protein Structure: Potential Biomarkers in Thyroid Cancer
  

  Oral Abstract Presenter: Bruno C. R Cateb, Medical Student

  Co-Author: Bruno C. R Cateb, Medical Student

  Co-Author: Karina C. Peres, Researcher – Laboratory of Cancer Molecular Genetics, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas/SP, Brazil

  Co-Author: Elisangela S. Teixeira, Doctoral student – Laboratory of Cancer Molecular Genetics, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas/SP, Brazil

  Senior Author/Primary Investigator: Natassia E. Bufalo, Researcher – Laboratory of Cancer Molecular Genetics, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas/SP, Brazil

  Co-Author: Natassia E. Bufalo, Researcher – Laboratory of Cancer Molecular Genetics, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas/SP, Brazil

  Senior Author/Primary Investigator: Laura S. Ward, Full Professor – Laboratory of Cancer Molecular Genetics, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas/SP, Brazil

  Co-Author: Laura S. Ward, Full Professor – Laboratory of Cancer Molecular Genetics, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas/SP, Brazil
• 2:15 PM - 2:30 PM CT

  Association of Sodium Iodide Symporter (NIS) Expression with 2025 American Thyroid Association (ATA) Guidelines Estimated Risk of Structural Recurrence
  

  Oral Abstract Presenter: Vidisha Master, MD – JOHNS HOPKINS HOSPITAL

  Co-Author: Wassim Najjar, MD – Johns Hopkins University School of Medicine

  Co-Author: Leila Mady, MD, PhD, MPH – Johns Hopkins University School of Medicine

  Co-Author: Mohammed Alshalalfa, PhD – Veracyte, Inc.

  Co-Author: Taylor Cavazos, PhD – Veracyte, Inc.

  Senior Author/Primary Investigator: Prasanna Santhanam, MBBS, MD – Johns Hopkins School of Medicine

  Co-Author: Paul Ladenson, MD – Johns Hopkins School of Medicine
• 2:30 PM - 2:45 PM CT

  Inhibition of mTOR Signaling Suppresses Growth and Downregulates Oxidative Phosphorylation of Lenvatinib Resistant Thyroid Cancer
  

  Oral Abstract Presenter: Sonam Kumari, PhD – NATIONAL INSTITUTES OF HEALTH

  Co-Author: Hu Zhu, PhD – National Center for Advancing Translational Sciences

  Co-Author: Christa Canagarajah, B.S. – National Center for Advancing Translational Sciences

  Co-Author: Min Shen, PhD – National Center for Advancing Translational Sciences

  Co-Author: Matthew Hall, PhD – National Center for Advancing Translational Sciences

  Senior Author/Primary Investigator: Joanna Klubo-Gwiezdzinska, MD, PhD, MHSc (she/her/hers) – NIH-NIDDK

  Co-Author: Joanna Klubo-Gwiezdzinska, MD, PhD, MHSc (she/her/hers) – NIH-NIDDK
• 2:45 PM - 3:00 PM CT

  Sentinel Lymph Node Biopsy Technique Based on Dual-Tracer Imaging and Deep Learning Method for Predicting Lymph Node Metastasis in cN0-PTC
  

  Oral Abstract Presenter: jing zhou, n/a – chongqing

  Senior Author/Primary Investigator: jing zhou, n/a – chongqing

  Co-Author: yuchen zhuang, n/a – chongqing

  Co-Author: qi xiao, n/a – The people’s Hospital of Yubei District of Chongqing City

  Co-Author: daxue li, n/a – chongqing women and children health center

  Senior Author/Primary Investigator: xinliang Su, n/a – The First Affiliated Hospital of Chongqing Medical University

  Co-Author: xinliang Su, n/a – The First Affiliated Hospital of Chongqing Medical University

  Senior Author/Primary Investigator: qian xiao, n/a – chongqing

  Co-Author: qian xiao, n/a – chongqing
• 3:00 PM - 3:15 PM CT

  Reproductive Milestones and Thyroid Cancer Risk in Women: Evidence from a Nationwide Cohort
  

  Oral Abstract Presenter: Jinyoung Kim, MD-PhD (she/her/hers) – The Catholic University of Korea

  Co-Author: Man Young Park, PhD – Korea Institute of Oriental Medicine

  Co-Author: Yuri Shin, BSc – The Catholic University of Korea

  Co-Author: Oakkee Hong, PhD – The Catholic University of Korea

  Co-Author: Jeongmin Lee, MD, PhD – The Catholic University of Korea

  Co-Author: Kwanhoon Jo, MD, PhD – The Catholic University of Korea

  Senior Author/Primary Investigator: Dong-Jun Lim, MD, PhD – The Catholic University of Korea