SY39 - Signal Strength: Wnt Pathways Powering Bone Formation

Sunday, June 14, 2026

4:30 PM - 6:00 PM CT

Location: Room W187

Symposium Chair(s)

Yumie Rhee, MD,PhD

Professor
Yonsei University College of Medicine
Seoul, South Korea

Disclosure(s): No financial relationships to disclose
Joy Wu, MD, PhD

Chief, Division of Endocrinology
Stanford University School of Medicine
Stanford, California, United States

Disclosure(s): Crinetics Pharmaceuticals: Advisory Board ()

Disclosure(s):

Yumie Rhee, MD,PhD: No financial relationships to disclose

Joy Y. Wu, MD, PhD: Crinetics Pharmaceuticals: Advisory Board ()

Wnt signaling has emerged as a cornerstone in skeletal biology, driving innovations in bone health and regenerative therapies. This symposium brings together leading experts to explore how Wnt pathways orchestrate cellular metabolism, mechanotransduction, and therapeutic strategies for bone formation.

Presentations:

4:30 PM - 5:00 PM CT

Harnessing Wnt Signaling for Anabolic Bone Regeneration
Symposium Speaker: Matthew Drake, MD, PhD – Hospital for Special Surgery
5:00 PM - 5:30 PM CT

Metabolic Integration by Wnt Signaling in Bone: Linking Cellular Bioenergetics to Anabolic Therapy
Symposium Speaker: Ryan C. Riddle, PhD (he/him/his) – University of Maryland School of Medicine
5:30 PM - 6:00 PM CT

Mechanotransduction and Wnt Signaling in Bone: Decoding the Skeleton’s Response to Load
Symposium Speaker: Alexander Robling, PhD